Thursday's game that pits the Milwaukee Brewers (86-66) against the St. Louis Cardinals (67-85) at Busch Stadium should be a close matchup based on our computer prediction, which projects a final score of 6-4 in favor of the Brewers. First pitch is at 1:15 PM ET on September 21.

The Cardinals will call on Miles Mikolas (7-12) against the Brewers and Wade Miley (8-4).

Cardinals vs. Brewers Game Info & Odds

  • When: Thursday, September 21, 2023 at 1:15 PM ET
  • Where: Busch Stadium in St. Louis, Missouri
  • How to Watch on TV: MLB Network
  • Live Stream: Watch this game on Fubo!

Bet on this matchup with BetMGM Sportsbook and use bonus code "GNPLAY" for special offers!

Cardinals vs. Brewers Score Prediction

Our prediction for this matchup is Brewers 6, Cardinals 5.

Total Prediction for Cardinals vs. Brewers

  • Total Prediction: Over 8.5 runs

Sportsbook Promo Codes

Discover More About This Game

Cardinals Performance Insights

  • Over the past 10 games, sportsbooks have not installed the Cardinals as the favorite once.
  • When it comes to hitting the over, St. Louis and its opponents are 5-5-0 in its last 10 games with a total.
  • The Cardinals have not played a game with a spread over their last 10 outings.
  • The Cardinals have been favorites in 69 games this season and won 32 (46.4%) of those contests.
  • This season St. Louis has won 32 of its 69 games, or 46.4%, when favored by at least -115 on the moneyline.
  • The sportsbooks' moneyline implies a 53.5% chance of a victory for the Cardinals.
  • St. Louis ranks 17th in the majors with 683 total runs scored this season.
  • The Cardinals have a 4.73 team ERA that ranks 23rd across all league pitching staffs.

Put your picks to the test and bet on with BetMGM Sportsbook. Use bonus code "GNPLAY" for special offers!

Cardinals Schedule

Date Opponent Score Pitching Matchup
September 16 Phillies L 6-1 Miles Mikolas vs Ranger Suárez
September 17 Phillies W 6-5 Dakota Hudson vs Taijuan Walker
September 18 Brewers W 1-0 Adam Wainwright vs Freddy Peralta
September 19 Brewers L 7-3 Drew Rom vs Trevor Megill
September 20 Brewers L 8-2 Zack Thompson vs Adrian Houser
September 21 Brewers - Miles Mikolas vs Wade Miley
September 22 @ Padres - Dakota Hudson vs Matt Waldron
September 23 @ Padres - Adam Wainwright vs Nick Martínez
September 24 @ Padres - Drew Rom vs Michael Wacha
September 26 @ Brewers - Zack Thompson vs Wade Miley
September 27 @ Brewers - Miles Mikolas vs Corbin Burnes